Liraglutide Biocon
Type 2 Diabetes Treatment
Liraglutide Biocon injection is a non-insulin injectable type used for treating type 2 diabetes mellitus in adults, adolescents, and children aged 10 years and older. It contains the active substance Liraglutide. It helps regulate blood sugar levels only when blood sugar is too high and offers cardiovascular benefits, making it a valuable option for managing diabetes and related complications.
Liraglutide Biocon injection is used on its own if your blood sugar is not properly controlled by diet and exercise alone, and you cannot use metformin (another diabetes medicine).
Liraglutide Biocon injection is used with other medicines for diabetes when they are not enough to control your blood sugar levels. These may include: oral antidiabetics (such as metformin, pioglitazone, sulfonylurea, sodium-glucose cotransporter 2 inhibitor (SGLT2i)) and/or insulin.
Primary Benefits of Liraglutide Biocon
Reduced blood sugar level
Reduced cardiovascular risks in patients with type 2 diabetes
Can be used alone (monotherapy) or combined with other diabetes medications
How Liraglutide Biocon Works
Liraglutide is a glucagon-like peptide-1 (GLP-1) analogue that closely resembles human GLP-1 and activates GLP-1 receptors, which are crucial for enhancing glucose-dependent insulin secretion from pancreatic beta cells.
Enhanced insulin secretion
Increases insulin release when blood sugar levels are high
Reduced glucagon levels
Lowers glucagon secretion, reducing excess glucose production in the liver.
Delayed gastric emptying
Slows food passage through the stomach, leading to gradual blood sugar release.
Appetite control
Regulates hunger, reducing overall body weight and fat mass over time.
These mechanisms collectively help stabilize blood sugar and reduce the frequency of glucose spikes. Clinical studies have shown that Liraglutide Biocon improves and sustains beta-cell function, crucial for long-term blood sugar management.
Effectiveness in Blood Sugar Reduction
- Monotherapy: Patients using Liraglutide as a monotherapy taken for 52 weeks, resulted in significant and sustained reductions of HbA1c levels compared with glimepiride.
- Combination Therapy: When combined with other type 2 diabetes medications (such as metformin, glimepiride, or SGLT2i), taken for 26 weeks, resulted in statistically significant and sustained reductions in HbA1c levels compared with patients receiving placebo.
Cardiovascular Benefits
A large cardiovascular outcomes trial was conducted with liraglutide in patients with type 2 diabetes mellitus who were at high cardiovascular risk. The patients treated with liraglutide showed no increase in cardiovascular risk against all comparators. This supports the drug’s effectiveness in reducing cardiovascular morbidity and mortality in high-risk patients.
Possible Side Effects
Like all medications, Liraglutide Biocon may cause side effects in some patients. Patients should consult their healthcare provider if they experience any adverse effects.
Common Side Effects
(may affect up to 1 in 10 people)
(may affect up to 1 in 10 people)
- Hypoglycemia: Symptoms may include cold sweat, cool pale skin, headache, fast heartbeat, feeling sick, extreme hunger, changes in vision, feeling sleepy, feeling weak, nervous, anxious, confused, difficulty concentrating, and shaking (tremors). A doctor will be able to treat low blood sugar and tell patients what to do if they notice these warning signs. This is more likely to happen if they also take a sulfonylurea or insulin. Doctors may reduce dosage of these medicines before patients start using Liraglutide Biocon.
- A doctor will be able to treat low blood sugar and tell patients what to do if they notice these warning signs. This is more likely to happen if they also take a sulfonylurea or insulin.
- Doctors may reduce dosage of these medicines before patients start using Liraglutide Biocon.
Rare Side Effects
(may affect up to 1 in 1,000 people)
(may affect up to 1 in 1,000 people)
- Severe Allergic Reaction (anaphylactic reaction) with additional symptoms including breathing problems, swelling of the throat and face, fast heartbeat, etc. Seek immediate medical attention if these occur.
- Bowel Obstruction: Severe constipation with stomach ache, bloating and vomiting. Contact your healthcare provider immediately if these symptoms arise.
Very Rare Side Effects
(may affect up to 1 in 10,000 people)
(may affect up to 1 in 10,000 people)
- Pancreatitis: Inflammation of the pancreas is a potentially life-threatening medical condition. Severe and persistent pain in the abdomen (stomach area) which might start from your back, as well as nausea and vomiting, could be a sign of an inflamed pancreas (pancreatitis).
Other Side Effects
Common
(may affect up to 1 in 10 people)
(may affect up to 1 in 10 people)
- Vomiting, headache, indigestion, heartburn
- Stomach pain or bloating, constipation, flatulence
- Decreased appetite, dizziness, increased pulse rate
- Cold symptoms, bronchitis
- Toothache, tiredness
- Injection site reactions (such as bruising or irritation)
- Increase in pancreatic enzymes
Uncommon
(may affect up to 1 in 100 people)
(may affect up to 1 in 100 people)
- Allergic reactions (e.g., itching, rash)
- Gallstones, inflamed gallbladder
- Dehydration (more common if experiencing nausea or vomiting)
- Malaise (feeling unwell)
- A delay in the emptying of the stomach
Important Safety Information
Patients should consult their healthcare provider before starting the treatment, especially if they have:
- A history of pancreatic diseases
- Heart conditions, particularly with a history of palpitations
- Gallbladder or thyroid issues