Dosage and Administration
About Biolide Injection
Biolide injection is provided as a clear, colorless (or nearly colorless) solution in a pre-filled device, intended for subcutaneous injection. Each device contains 3 ml of solution and is designed to deliver doses of 0.6 mg, 1.2 mg, 1.8 mg, 2.4 mg, and 3.0 mg.
Available pack sizes
Biolide is available in packs of 1, 3, or 5 devices (not all pack sizes may be marketed).
Needles not included
The injection device does not come with needles. Suitable options include BD Ultra-Fine® or NovoFine® disposable needles, available in 32G and up to 8 mm in length.
The injection can be administered once daily at any time of the day, independent of meals. Before first-time use, patients will receive instructions on using the device correctly from their healthcare provider.
Recommended Dosage
Starting dose
0.6 mg once daily, to be taken for at least one week, with gradual increases as advised by a physician.
Maximum dose
3.0 mg once daily (adjustments made as per physician’s guidance).
Instructions for Use
Examine the Device
Examine the Device- Check the name and colored label of your device, to make sure that it contains Liraglutide
- Remove the device cap. The solution should appear clear and colorless. Do not use if the solution is frozen or cloudy.
Select Injection Area
Select Injection Area - Recommended areas for subcutaneous injection include the abdomen, thighs, or upper arms. Rotate between different sites to prevent irritation. Consult a healthcare provider for guidance on the best site for you.
Attach the Needle
Attach the Needle - Remove the paper tab from a new disposable needle and attach it tightly onto the device.
- Pull off the outer needle cap, set it aside, then remove and discard the inner needle cap.
Important: Always use a new needle for each injection and avoid using bent or damaged needles.
Check the Device Flow
Check the Device Flow - Check the flow of the device before the first injection. Turn the dose selector to align with the flow check symbol.
- With the needle pointing upward, gently tap the cartridge to gather any air bubbles.
- Press the dose button until ‘0 mg’ aligns with the pointer. A drop of solution should appear at the needle tip; if not, repeat the step up to four times. If no drop appears after multiple attempts, replace the needle and repeat.
Set the Dose
Set the Dose - Verify that the pointer aligns with ‘0 mg’.
- Turn the dose selector to the prescribed dose (0.6 mg, 1.2 mg, 1.8 mg, 2.4 mg, or 3.0 mg).
- Always use the dose counter and dose pointer to see how much mg you have selected before injecting this medicine.
Inject the Dose
Inject the Dose - Insert the needle into the skin using the injection technique advised by your healthcare provider.
- Press and hold the dose button until ‘0 mg’ aligns with the pointer.
- Keep the needle under the skin for at least 6 seconds to ensure that the full dose is administered.
- Always watch the dose counter to know how many mg you inject.
Post-Injection Precautions
Post-Injection Precautions - Remove the needle, place the outer needle cap back on, and unscrew it from the device. Dispose of the needle carefully.
- Replace the device cap and store the device as per guidelines (refer to the ‘Storage of Biolide Injection’ section).
Taking Care of the Device
- Avoid exposure to extreme temperatures. Do not leave the device in areas where it may become too hot or too cold.
- Do not inject if the solution has been frozen.
- Keep the device away from dust, dirt, and liquids.
- Use a mild detergent on a moist cloth to clean the device if necessary. Do not soak, wash, or lubricate the device.
- Avoid dropping or damaging the device. Do not refill or attempt repairs on the device once it is empty.
Storage of Biolide Injection
Before First Use
Store in a refrigerator between 2°C and 8°C. Avoid freezing and keep it away from the freezer compartment.
After First Use
Store at a temperature below 30°C or in a refrigerator (2°C to 8°C). Keep away from the freezer compartment and do not freeze.
Device Cap
Always keep the device cap on when not in use to protect it from light.
Dispose Properly
Do not throw away any medicine or used devices via household waste. Consult a pharmacist on how to dispose of Biolide safely.